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Receptor-kinase EGFR-MAPK adaptor proteins mediate the epithelial response to Candida albicans via the cytolytic peptide toxin, candidalysin

Candida albicans (C. albicans) is a dimorphic commensal human fungal pathogen that can cause severe oropharyngeal candidiasis (oral thrush) in susceptible hosts. During invasive infection, C. albicans hyphae invade oral epithelial cells (OECs) and secrete candidalysin, a pore-forming cytolytic pepti...

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Detalles Bibliográficos
Autores principales:	Ponde, Nicole O., Lortal, Léa, Tsavou, Antzela, Hepworth, Olivia W., Wickramasinghe, Don N., Ho, Jemima, Richardson, Jonathan P., Moyes, David L., Gaffen, Sarah L., Naglik, Julian R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530844/ https://www.ncbi.nlm.nih.gov/pubmed/36037968 http://dx.doi.org/10.1016/j.jbc.2022.102419

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