Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C isozymes are involved in mGlu(5a) receptor internalization

The internalization of G protein–coupled receptors (GPCRs) can be regulated by PKC. However, most tools available to study the contribution of PKC isozymes have considerable limitations, including a lack of selectivity. In this study, we generated and characterized human embryonic kidney 293A (HEK29...

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Detalles Bibliográficos
Autores principales: van Senten, Jeffrey R., Møller, Thor C., Moo, Ee Von, Seiersen, Sofie D., Bräuner-Osborne, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530845/
https://www.ncbi.nlm.nih.gov/pubmed/36087841
http://dx.doi.org/10.1016/j.jbc.2022.102466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530845/
https://www.ncbi.nlm.nih.gov/pubmed/36087841
http://dx.doi.org/10.1016/j.jbc.2022.102466

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