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Leukocyte cell-derived chemotaxin 2 regulates epithelial-mesenchymal transition and cancer stemness in hepatocellular carcinoma

Leukocyte cell-derived chemotaxin 2 (LECT2) acts as a tumor suppressor in hepatocellular carcinoma (HCC). However, the antineoplastic mechanism of LECT2, especially its influence on hepatic cancer stem cells (CSCs), remains largely unknown. In The Cancer Genome Atlas cohort, LECT2 mRNA expression wa...

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Detalles Bibliográficos
Autores principales: Chu, Tian-Huei, Ko, Chou-Yuan, Tai, Po-Han, Chang, Yi-Chen, Huang, Chao-Cheng, Wu, Tung-Yang, Chan, Hoi-Hung, Wu, Ping-Hsuan, Weng, Chien-Hui, Lin, Yu-Wei, Kung, Mei-Lang, Fang, Cheng-Chieh, Wu, Jian-Ching, Wen, Zhi-Hong, Lee, Yung-Kuo, Hu, Tsung-Hui, Tai, Ming-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9530851/
https://www.ncbi.nlm.nih.gov/pubmed/36055405
http://dx.doi.org/10.1016/j.jbc.2022.102442