Cargando…
Influence of denaturants on amyloid β42 aggregation kinetics
Amyloid formation is linked to devastating neurodegenerative diseases, motivating detailed studies of the mechanisms of amyloid formation. For Aβ, the peptide associated with Alzheimer’s disease, the mechanism and rate of aggregation have been established for a range of variants and conditions in vi...
Autores principales: | Weiffert, Tanja, Meisl, Georg, Curk, Samo, Cukalevski, Risto, Šarić, Anđela, Knowles, Tuomas P. J., Linse, Sara |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531139/ https://www.ncbi.nlm.nih.gov/pubmed/36203800 http://dx.doi.org/10.3389/fnins.2022.943355 |
Ejemplares similares
-
Ultrastructural evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils
por: Törnquist, Mattias, et al.
Publicado: (2020) -
Distinct thermodynamic signature of oligomer generation in the aggregation of the amyloid-β peptide
por: Cohen, Samuel I. A., et al.
Publicado: (2018) -
The Aβ40 and Aβ42 peptides self-assemble into separate homomolecular fibrils in binary mixtures but cross-react during primary nucleation
por: Cukalevski, Risto, et al.
Publicado: (2015) -
On the role of sidechain size and charge in the aggregation of Aβ42 with familial mutations
por: Yang, Xiaoting, et al.
Publicado: (2018) -
Identification of on- and off-pathway oligomers in amyloid fibril formation
por: Dear, Alexander J., et al.
Publicado: (2020)