Differential activity of mGlu(7) allosteric modulators provides evidence for mGlu(7/8) heterodimers at hippocampal Schaffer collateral-CA1 synapses

Glutamate acts at eight metabotropic glutamate (mGlu) receptor subtypes expressed in a partially overlapping fashion in distinct brain circuits. Recent evidence indicates that specific mGlu receptor protomers can heterodimerize and that these heterodimers can exhibit different pharmacology when comp...

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Detalles Bibliográficos
Autores principales: Lin, Xin, Fisher, Nicole M., Dogra, Shalini, Senter, Rebecca K., Reed, Carson W., Kalbfleisch, Jacob J., Lindsley, Craig W., Asher, Wesley B., Xiang, Zixiu, Niswender, Colleen M., Javitch, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Accelerated Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531177/
https://www.ncbi.nlm.nih.gov/pubmed/36063995
http://dx.doi.org/10.1016/j.jbc.2022.102458

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