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Complement-mediated serum bactericidal activity of antibodies elicited by the Shigella sonnei GMMA vaccine in adults from a shigellosis-endemic country: Exploratory analysis of a Phase 2a randomized study
Shigella is associated with a significant burden of disease worldwide among individuals of all ages and is the major cause of moderate and severe diarrhea in children under five years of age in low- and middle-income countries. Several candidate vaccines against Shigella species are currently under...
Autores principales: | Kapulu, Melissa C., Nakakana, Usman, Sciré, Antonella S., Sarakinou, Eleanna, Conti, Valentino, Rossi, Omar, Acquaviva, Alessandra, Necchi, Francesca, Obiero, Christina W., Martin, Laura B., Bejon, Philip, Njuguna, Patricia, Micoli, Francesca, Podda, Audino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531247/ https://www.ncbi.nlm.nih.gov/pubmed/36203568 http://dx.doi.org/10.3389/fimmu.2022.971866 |
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