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Metal-free synthesis of 3-trifluoromethyl-1,2,4-triazoles via multi-component reaction of trifluoroacetimidoyl chlorides, hydrazine hydrate and benzene-1,3,5-triyl triformate

A convenient approach for the construction of pharmaceutically valuable 3-trifluoromethyl-1,2,4-triazoles has been developed, which employs the readily available trifluoroacetimidoyl chlorides, hydrazine hydrate and benzene-1,3,5-triyl triformate (TFBen) as starting materials. The multi-component re...

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Detalles Bibliográficos
Autores principales:	Wang, Binjie, Sun, Yue, Cheng, An, Zhu, Yeanlun, Wang, Jiye, Chen, Zhengkai, Wu, Xiao-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531263/ https://www.ncbi.nlm.nih.gov/pubmed/36204143 http://dx.doi.org/10.3389/fchem.2022.1013977

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