Synergistic prostaglandin E synthesis by myeloid and endothelial cells promotes fetal hematopoietic stem cell expansion in vertebrates

During development, hematopoietic stem cells (HSCs) are produced from the hemogenic endothelium and will expand in a transient hematopoietic niche. Prostaglandin E(2) (PGE2) is essential during vertebrate development and HSC specification, but its precise source in the embryo remains elusive. Here,...

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Detalles Bibliográficos
Autores principales: Cacialli, Pietro, Mailhe, Marie‐Pierre, Wagner, Ingrid, Merkler, Doron, Golub, Rachel, Bertrand, Julien Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531293/
https://www.ncbi.nlm.nih.gov/pubmed/35924455
http://dx.doi.org/10.15252/embj.2021108536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531293/
https://www.ncbi.nlm.nih.gov/pubmed/35924455
http://dx.doi.org/10.15252/embj.2021108536

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