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Regulation of membrane fluidity by RNF145‐triggered degradation of the lipid hydrolase ADIPOR2
The regulation of membrane lipid composition is critical for cellular homeostasis. Cells are particularly sensitive to phospholipid saturation, with increased saturation causing membrane rigidification and lipotoxicity. How mammalian cells sense membrane lipid composition and reverse fatty acid (FA)...
Autores principales: | Volkmar, Norbert, Gawden‐Bone, Christian M, Williamson, James C, Nixon‐Abell, Jonathon, West, James A, St George‐Hyslop, Peter H, Kaser, Arthur, Lehner, Paul J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531299/ https://www.ncbi.nlm.nih.gov/pubmed/35993436 http://dx.doi.org/10.15252/embj.2022110777 |
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