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Endosome maturation links PI3Kα signaling to lysosome repopulation during basal autophagy

Autophagy depends on the repopulation of lysosomes to degrade intracellular components and recycle nutrients. How cells co‐ordinate lysosome repopulation during basal autophagy, which occurs constitutively under nutrient‐rich conditions, is unknown. Here, we identify an endosome‐dependent phosphoino...

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Detalles Bibliográficos
Autores principales: Rodgers, Samuel J, Jones, Emily I, Arumugam, Senthil, Hamila, Sabryn A, Danne, Jill, Gurung, Rajendra, Eramo, Matthew J, Nanayakkara, Randini, Ramm, Georg, McGrath, Meagan J, Mitchell, Christina A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531306/
https://www.ncbi.nlm.nih.gov/pubmed/35968799
http://dx.doi.org/10.15252/embj.2021110398