Cargando…
Endosome maturation links PI3Kα signaling to lysosome repopulation during basal autophagy
Autophagy depends on the repopulation of lysosomes to degrade intracellular components and recycle nutrients. How cells co‐ordinate lysosome repopulation during basal autophagy, which occurs constitutively under nutrient‐rich conditions, is unknown. Here, we identify an endosome‐dependent phosphoino...
Autores principales: | Rodgers, Samuel J, Jones, Emily I, Arumugam, Senthil, Hamila, Sabryn A, Danne, Jill, Gurung, Rajendra, Eramo, Matthew J, Nanayakkara, Randini, Ramm, Georg, McGrath, Meagan J, Mitchell, Christina A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531306/ https://www.ncbi.nlm.nih.gov/pubmed/35968799 http://dx.doi.org/10.15252/embj.2021110398 |
Ejemplares similares
-
Autophagic lysosome reformation in health and disease
por: Nanayakkara, Randini, et al.
Publicado: (2022) -
INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer
por: Rodgers, Samuel J., et al.
Publicado: (2021) -
Defective lysosome reformation during autophagy causes skeletal muscle disease
por: McGrath, Meagan J., et al.
Publicado: (2021) -
Altered endosomal-lysosomal biogenesis in melanoma
por: Lam, Giang T., et al.
Publicado: (2023) -
Translocation and clustering of endosomes and lysosomes depends on microtubules
Publicado: (1987)