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H3K18 lactylation marks tissue-specific active enhancers

BACKGROUND: Histone lactylation has been recently described as a novel histone post-translational modification linking cellular metabolism to epigenetic regulation. RESULTS: Given the expected relevance of this modification and current limited knowledge of its function, we generate genome-wide datas...

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Detalles Bibliográficos
Autores principales: Galle, Eva, Wong, Chee-Wai, Ghosh, Adhideb, Desgeorges, Thibaut, Melrose, Kate, Hinte, Laura C., Castellano-Castillo, Daniel, Engl, Magdalena, de Sousa, Joao Agostinho, Ruiz-Ojeda, Francisco Javier, De Bock, Katrien, Ruiz, Jonatan R., von Meyenn, Ferdinand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531456/
https://www.ncbi.nlm.nih.gov/pubmed/36192798
http://dx.doi.org/10.1186/s13059-022-02775-y