[3 + 2] cycloaddition of nonstabilized azomethine ylides and 2-benzothiazolamines to access imidazolidine derivatives

A simple and practical method for the construction of 1,3,5-trisubstituted imidazolidine derivatives via [3 + 2] cycloaddition reaction has been developed. This reaction could smoothly proceed between nonstabilized azomethine ylides generated in situ and 2-benzothiazolamines to deliver a wide scope...

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Detalles Bibliográficos
Autores principales: Wang, Kai-Kai, Li, Yan-Li, Wang, Ming-Yue, Jing, Jun, Wang, Zhan-Yong, Chen, Rongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531537/
https://www.ncbi.nlm.nih.gov/pubmed/36320509
http://dx.doi.org/10.1039/d2ra04616d
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author Wang, Kai-Kai
Li, Yan-Li
Wang, Ming-Yue
Jing, Jun
Wang, Zhan-Yong
Chen, Rongxiang
author_facet Wang, Kai-Kai
Li, Yan-Li
Wang, Ming-Yue
Jing, Jun
Wang, Zhan-Yong
Chen, Rongxiang
author_sort Wang, Kai-Kai
collection PubMed
description A simple and practical method for the construction of 1,3,5-trisubstituted imidazolidine derivatives via [3 + 2] cycloaddition reaction has been developed. This reaction could smoothly proceed between nonstabilized azomethine ylides generated in situ and 2-benzothiazolamines to deliver a wide scope of differently substituted imidazolidines in high yields (up to 98%). The structure of one example was confirmed by X-ray single-crystal structure analysis.
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spelling pubmed-95315372022-10-31 [3 + 2] cycloaddition of nonstabilized azomethine ylides and 2-benzothiazolamines to access imidazolidine derivatives Wang, Kai-Kai Li, Yan-Li Wang, Ming-Yue Jing, Jun Wang, Zhan-Yong Chen, Rongxiang RSC Adv Chemistry A simple and practical method for the construction of 1,3,5-trisubstituted imidazolidine derivatives via [3 + 2] cycloaddition reaction has been developed. This reaction could smoothly proceed between nonstabilized azomethine ylides generated in situ and 2-benzothiazolamines to deliver a wide scope of differently substituted imidazolidines in high yields (up to 98%). The structure of one example was confirmed by X-ray single-crystal structure analysis. The Royal Society of Chemistry 2022-10-04 /pmc/articles/PMC9531537/ /pubmed/36320509 http://dx.doi.org/10.1039/d2ra04616d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Wang, Kai-Kai
Li, Yan-Li
Wang, Ming-Yue
Jing, Jun
Wang, Zhan-Yong
Chen, Rongxiang
[3 + 2] cycloaddition of nonstabilized azomethine ylides and 2-benzothiazolamines to access imidazolidine derivatives
title [3 + 2] cycloaddition of nonstabilized azomethine ylides and 2-benzothiazolamines to access imidazolidine derivatives
title_full [3 + 2] cycloaddition of nonstabilized azomethine ylides and 2-benzothiazolamines to access imidazolidine derivatives
title_fullStr [3 + 2] cycloaddition of nonstabilized azomethine ylides and 2-benzothiazolamines to access imidazolidine derivatives
title_full_unstemmed [3 + 2] cycloaddition of nonstabilized azomethine ylides and 2-benzothiazolamines to access imidazolidine derivatives
title_short [3 + 2] cycloaddition of nonstabilized azomethine ylides and 2-benzothiazolamines to access imidazolidine derivatives
title_sort [3 + 2] cycloaddition of nonstabilized azomethine ylides and 2-benzothiazolamines to access imidazolidine derivatives
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531537/
https://www.ncbi.nlm.nih.gov/pubmed/36320509
http://dx.doi.org/10.1039/d2ra04616d
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