Translatome profiling in fatal familial insomnia implicates TOR signaling in somatostatin neurons

Selective neuronal vulnerability is common in neurodegenerative diseases but poorly understood. In genetic prion diseases, including fatal familial insomnia (FFI) and Creutzfeldt–Jakob disease (CJD), different mutations in the Prnp gene manifest as clinically and neuropathologically distinct disease...

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Detalles Bibliográficos
Autores principales: Bauer, Susanne, Dittrich, Lars, Kaczmarczyk, Lech, Schleif, Melvin, Benfeitas, Rui, Jackson, Walker S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531780/
https://www.ncbi.nlm.nih.gov/pubmed/36192034
http://dx.doi.org/10.26508/lsa.202201530

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