Sir2 and Reb1 antagonistically regulate nucleosome occupancy in subtelomeric X-elements and repress TERRAs by distinct mechanisms

Telomere chromatin structure is pivotal for maintaining genome stability by regulating the binding of telomere-associated proteins and inhibiting the DNA damage response. In Saccharomyces cerevisiae, silent information regulator (Sir) proteins bind to terminal repeats and to subtelomeric X-elements,...

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Detalles Bibliográficos
Autores principales: Bauer, Stefanie L., Grochalski, Thomas N. T., Smialowska, Agata, Åström, Stefan U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531808/
https://www.ncbi.nlm.nih.gov/pubmed/36137093
http://dx.doi.org/10.1371/journal.pgen.1010419

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