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Ecdysone signaling mediates the trade-off between immunity and reproduction via suppression of amyloids in the mosquito Aedes aegypti

The balance between immunity and reproduction is essential for many key physiological functions. We report that to maintain an optimal fertility, 20-hydroxyecdysone (20E) and the ecdysone receptor (EcR) downregulate the immune deficiency (IMD) pathway during the post blood meal phase (PBM) of the Ae...

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Detalles Bibliográficos
Autores principales: Wang, Mao, Wang, Yanhong, Chang, Mengmeng, Wang, Xueli, Shi, Zuokun, Raikhel, Alexander S., Zou, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531809/
https://www.ncbi.nlm.nih.gov/pubmed/36137163
http://dx.doi.org/10.1371/journal.ppat.1010837