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Ecdysone signaling mediates the trade-off between immunity and reproduction via suppression of amyloids in the mosquito Aedes aegypti
The balance between immunity and reproduction is essential for many key physiological functions. We report that to maintain an optimal fertility, 20-hydroxyecdysone (20E) and the ecdysone receptor (EcR) downregulate the immune deficiency (IMD) pathway during the post blood meal phase (PBM) of the Ae...
Autores principales: | Wang, Mao, Wang, Yanhong, Chang, Mengmeng, Wang, Xueli, Shi, Zuokun, Raikhel, Alexander S., Zou, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531809/ https://www.ncbi.nlm.nih.gov/pubmed/36137163 http://dx.doi.org/10.1371/journal.ppat.1010837 |
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