AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewing’s sarcoma cells

Ewing’s sarcoma is the second most common bone malignancy in children or young adults and is caused by an oncogenic transcription factor by a chromosomal translocation between the EWSR1 gene and the ETS transcription factor family. However, the transcriptional mechanism of EWS-ETS fusion proteins is...

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Detalles Bibliográficos
Autores principales: Kitagawa, Takao, Kobayashi, Daiki, Baron, Byron, Okita, Hajime, Miyamoto, Tatsuo, Takai, Rie, Paudel, Durga, Ohta, Tohru, Asaoka, Yoichi, Tokunaga, Masayuki, Nakagawa, Koji, Furutani-Seiki, Makoto, Araki, Norie, Kuramitsu, Yasuhiro, Kobayashi, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531837/
https://www.ncbi.nlm.nih.gov/pubmed/36194562
http://dx.doi.org/10.1371/journal.pone.0269077

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