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Endogenous Interleukin-17a Contributes to Normal Spatial Memory Retention but Does Not Affect Early Behavioral or Neuropathological Outcomes after Experimental Traumatic Brain Injury
Interleukin-17 (IL-17) is a proinflammatory cytokine primarily secreted in the brain by inflammatory T lymphocytes and glial cells. IL-17(+) T-helper (Th17) cells are increased in the ipsilateral hemisphere after experimental traumatic brain injury (TBI), and IL-17 levels are increased in serum and...
Autores principales: | Simon, Dennis W., Raphael, Itay, Johnson, Kendall M., Dixon, C. Edward, Vagni, Vincent, Janesko-Feldman, Keri, Kochanek, Patrick M., Bayir, Hülya, Clark, Robert S.B., McGeachy, Mandy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531893/ https://www.ncbi.nlm.nih.gov/pubmed/36204388 http://dx.doi.org/10.1089/neur.2022.0017 |
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