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A partially nested cortical hierarchy of neural states underlies event segmentation in the human brain

A fundamental aspect of human experience is that it is segmented into discrete events. This may be underpinned by transitions between distinct neural states. Using an innovative data-driven state segmentation method, we investigate how neural states are organized across the cortical hierarchy and wh...

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Autores principales: Geerligs, Linda, Gözükara, Dora, Oetringer, Djamari, Campbell, Karen L, van Gerven, Marcel, Güçlü, Umut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531941/
https://www.ncbi.nlm.nih.gov/pubmed/36111671
http://dx.doi.org/10.7554/eLife.77430
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author Geerligs, Linda
Gözükara, Dora
Oetringer, Djamari
Campbell, Karen L
van Gerven, Marcel
Güçlü, Umut
author_facet Geerligs, Linda
Gözükara, Dora
Oetringer, Djamari
Campbell, Karen L
van Gerven, Marcel
Güçlü, Umut
author_sort Geerligs, Linda
collection PubMed
description A fundamental aspect of human experience is that it is segmented into discrete events. This may be underpinned by transitions between distinct neural states. Using an innovative data-driven state segmentation method, we investigate how neural states are organized across the cortical hierarchy and where in the cortex neural state boundaries and perceived event boundaries overlap. Our results show that neural state boundaries are organized in a temporal cortical hierarchy, with short states in primary sensory regions, and long states in lateral and medial prefrontal cortex. State boundaries are shared within and between groups of brain regions that resemble well-known functional networks. Perceived event boundaries overlap with neural state boundaries across large parts of the cortical hierarchy, particularly when those state boundaries demarcate a strong transition or are shared between brain regions. Taken together, these findings suggest that a partially nested cortical hierarchy of neural states forms the basis of event segmentation.
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spelling pubmed-95319412022-10-05 A partially nested cortical hierarchy of neural states underlies event segmentation in the human brain Geerligs, Linda Gözükara, Dora Oetringer, Djamari Campbell, Karen L van Gerven, Marcel Güçlü, Umut eLife Neuroscience A fundamental aspect of human experience is that it is segmented into discrete events. This may be underpinned by transitions between distinct neural states. Using an innovative data-driven state segmentation method, we investigate how neural states are organized across the cortical hierarchy and where in the cortex neural state boundaries and perceived event boundaries overlap. Our results show that neural state boundaries are organized in a temporal cortical hierarchy, with short states in primary sensory regions, and long states in lateral and medial prefrontal cortex. State boundaries are shared within and between groups of brain regions that resemble well-known functional networks. Perceived event boundaries overlap with neural state boundaries across large parts of the cortical hierarchy, particularly when those state boundaries demarcate a strong transition or are shared between brain regions. Taken together, these findings suggest that a partially nested cortical hierarchy of neural states forms the basis of event segmentation. eLife Sciences Publications, Ltd 2022-09-16 /pmc/articles/PMC9531941/ /pubmed/36111671 http://dx.doi.org/10.7554/eLife.77430 Text en © 2022, Geerligs et al https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Neuroscience
Geerligs, Linda
Gözükara, Dora
Oetringer, Djamari
Campbell, Karen L
van Gerven, Marcel
Güçlü, Umut
A partially nested cortical hierarchy of neural states underlies event segmentation in the human brain
title A partially nested cortical hierarchy of neural states underlies event segmentation in the human brain
title_full A partially nested cortical hierarchy of neural states underlies event segmentation in the human brain
title_fullStr A partially nested cortical hierarchy of neural states underlies event segmentation in the human brain
title_full_unstemmed A partially nested cortical hierarchy of neural states underlies event segmentation in the human brain
title_short A partially nested cortical hierarchy of neural states underlies event segmentation in the human brain
title_sort partially nested cortical hierarchy of neural states underlies event segmentation in the human brain
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531941/
https://www.ncbi.nlm.nih.gov/pubmed/36111671
http://dx.doi.org/10.7554/eLife.77430
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