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CHCHD2 maintains mitochondrial contact site and cristae organizing system stability and protects against mitochondrial dysfunction in an experimental model of Parkinson's disease

BACKGROUND: Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's dementia. Mitochondrial dysfunction is involved in the pathology of PD. Coiled-coil-helix-coiled-coil-helix domain-containing 2 (CHCHD2) was identified as associated with autosomal do...

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Detalles Bibliográficos
Autores principales: Lu, Lin, Mao, Hengxu, Zhou, Miaomiao, Lin, Yuwan, Dai, Wei, Qiu, Jiewen, Xiao, Yousheng, Mo, Mingshu, Zhu, Xiaoqin, Wu, Zhuohua, Pei, Zhong, Guo, Wenyuan, Xu, Pingyi, Chen, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532036/
https://www.ncbi.nlm.nih.gov/pubmed/35830185
http://dx.doi.org/10.1097/CM9.0000000000002053

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