Donor genetic determinant of thymopoiesis rs2204985 impacts clinical outcome after single HLA mismatched hematopoietic stem cell transplantation

A common genetic variant within the T cell receptor alpha (TCRA)-T cell receptor delta (TCRD) locus (rs2204985) has been recently found to associate with thymic function. Aim of this study was to investigate the potential impact of donor rs2204985 genotype on patient’s outcome after unrelated hemato...

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Detalles Bibliográficos
Autores principales: Tsamadou, Chrysanthi, Gowdavally, Sowmya, Platzbecker, Uwe, Sala, Elisa, Valerius, Thomas, Wagner-Drouet, Eva, Wulf, Gerald, Kröger, Nicolaus, Murawski, Niels, Einsele, Hermann, Schaefer-Eckart, Kerstin, Freitag, Sebastian, Casper, Jochen, Kaufmann, Martin, Dürholt, Mareike, Hertenstein, Bernd, Klein, Stefan, Ringhoffer, Mark, Frank, Sandra, Neuchel, Christine, Rode, Immanuel, Schrezenmeier, Hubert, Mytilineos, Joannis, Fuerst, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532242/
https://www.ncbi.nlm.nih.gov/pubmed/35804057
http://dx.doi.org/10.1038/s41409-022-01751-1

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