Cargando…

Profiling Disease and Economic Burden in CRSwNP Using Machine Learning

PURPOSE: Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with high healthcare resource utilization (HRU) and economic cost; however, heterogeneity of clinical burden among patients with differing clinical characteristics has not been fully elucidated. Here, an unsupervised machine le...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bhattacharyya, Neil, Silver, Jared, Bogart, Michael, Kponee-Shovein, Kalé, Cheng, Wendy Y, Cheng, Mu, Cheung, Hoi Ching, Duh, Mei Sheng, Hahn, Beth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532264/ https://www.ncbi.nlm.nih.gov/pubmed/36211639 http://dx.doi.org/10.2147/JAA.S378469

Ejemplares similares

EUFOREA consensus on biologics for CRSwNP with or without asthma
por: Fokkens, Wytske J., et al.
Publicado: (2019)

Clinical characteristics of patients with CRSwNP with intensely high eosinophil level
por: Ma, Ling, et al.
Publicado: (2022)

Adverse events for biologics in patients with CRSwNP: A meta‐analysis
por: Shen, Yang, et al.
Publicado: (2022)

Nasal cytology and histology in CRSwNP: Two sides of the same coin
por: Gelardi, Matteo, et al.
Publicado: (2023)

Differences in men and women suffering from CRSwNP and AERD in quality of life
por: Bartosik, Tina J., et al.
Publicado: (2020)

Rapid and Continuing Improvements in Nasal Symptoms with Dupilumab in Patients with Severe CRSwNP
por: Bachert, Claus, et al.
Publicado: (2022)

Guideline for the use of immunobiologicals in chronic rhinosinusitis with nasal polyps (CRSwNP) in Brazil
por: Anselmo-Lima, Wilma T., et al.
Publicado: (2021)

Olfaction Recovery following Dupilumab Is Independent of Nasal Polyp Reduction in CRSwNP
por: Cantone, Elena, et al.
Publicado: (2022)

Measuring Nasal Patency and the Sense of Smell in CRSwNP Patients Treated with Dupilumab
por: Ottaviano, Giancarlo, et al.
Publicado: (2023)

Eosinophil Cationic Protein Variation in Patients with Asthma and CRSwNP Treated with Dupilumab
por: Ledda, Andrea Giovanni, et al.
Publicado: (2023)

Comparison of different medical treatment options for CRSwNP: doxycycline, methylprednisolone, mepolizumab and omalizumab
por: De Schryver, Els, et al.
Publicado: (2015)

Real‐life effectiveness of biological therapies on symptoms in severe asthma with comorbid CRSwNP
por: Mümmler, Carlo, et al.
Publicado: (2021)

Necroptosis Underlies Neutrophilic Inflammation Associated with the Chronic Rhinosinusitis with Nasal Polyps (CRSwNP)
por: Xie, Yadong, et al.
Publicado: (2021)

Dupilumab in CRSwNP: Responder Analysis Using Clinically Meaningful Efficacy Outcome Thresholds
por: Chuang, Chien‐Chia, et al.
Publicado: (2021)

Effectiveness of Dupilumab in the Treatment of Adult and Older Adult Patients with Severe, Uncontrolled CRSwNP
por: Ottaviano, Giancarlo, et al.
Publicado: (2023)

Eosinophil-mast cell pattern of intraepithelial infiltration as a marker of severity in CRSwNP
por: Gelardi, Matteo, et al.
Publicado: (2023)

The argument against the use of dupilumab in patients with limited polyp burden in chronic rhinosinusitis with nasal polyposis (CRSwNP)
por: Hardison, Scott A., et al.
Publicado: (2023)

WITHDRAWN: Dupilumab: A review of potential in the treatment of Chronic rhinosinusitis with nasal polyps (CRSwNP)
por: Sree Sudha, T.Y., et al.
Publicado: (2020)

Epithelial immune regulation of inflammatory airway diseases: Chronic rhinosinusitis with nasal polyps (CRSwNP)
por: Klimek, Ludger, et al.
Publicado: (2022)

Real-life effectiveness of dupilumab in patients with mild to moderate bronchial asthma comorbid with CRSwNP
por: Minagawa, Shunsuke, et al.
Publicado: (2022)

Cost–Utility Analysis of Dupilumab for the Treatment of Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) in Italy
por: De Corso, Eugenio, et al.
Publicado: (2022)

Calprotectin in nasal secretion: a new biomarker of non-type 2 inflammation in CRSwNP
por: De Corso, Eugenio, et al.
Publicado: (2022)

The “real life” efficacy of dupilumab is independent of initial polyp size and concomitant steroids in CRSwNP
por: Campion, Nicholas J., et al.
Publicado: (2023)

Efficacy of Biologics on Refractory Eosinophilic Otitis Media Associated with Bronchial Asthma or Severe Uncontrolled CRSwNP
por: De Corso, Eugenio, et al.
Publicado: (2022)

How to manage recurrences after surgery in CRSwNP patients in the biologic era: a narrative review
por: De Corso, Eugenio, et al.
Publicado: (2023)

Real-world evidence for the effectiveness and safety of dupilumab in patients with CRSwNP after 1 year of therapy
por: Albrecht, Tobias, et al.
Publicado: (2023)

Targeting IL-4 and IL-13 Receptors on Eosinophils in CRSwNP Patients: The Clinical Efficacy of Dupilumab
por: Piazzetta, Giovanna Lucia, et al.
Publicado: (2023)

Checklist for the Multidisciplinary Approach to United Airway in Patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) and asthma
por: Castillo Vizuete, José Antonio, et al.
Publicado: (2022)

A retrospective, cross-sectional study reveals that women with CRSwNP have more severe disease than men
por: Stevens, Whitney W, et al.
Publicado: (2015)

Computational fluid dynamic modeling of the effect of dupilumab in the management of anosmia secondary to chronic rhinosinusitis with nasal polyps (CRSwNP)
por: Lepley, Thomas J., et al.
Publicado: (2022)

Effectiveness of Dupilumab in the Treatment of Patients with Severe Uncontrolled CRSwNP: A “Real-Life” Observational Study in the First Year of Treatment
por: De Corso, Eugenio, et al.
Publicado: (2022)

A Randomized Clinical Trial of Elemental Zinc Add-on Therapy on Clinical Outcomes of Patients with Chronic Rhinosinusitis with Nasal Polyposis (CRSwNP)
por: Akbari Dilmaghani, Nader, et al.
Publicado: (2019)

Effectiveness of Dupilumab in the Treatment of Patients with Uncontrolled Severe CRSwNP: A “Real-Life” Observational Study in Naïve and Post-Surgical Patients
por: Ottaviano, Giancarlo, et al.
Publicado: (2022)

Are objective ‘findings’ the same as subjective ‘severity’? A study of the relationship between computed tomography findings and subjective severity in preoperative CRSwNP patients
por: Lu, Hanyu, et al.
Publicado: (2020)

Management of Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) in the Pan-Arab Region: Consensus Recommendations from a Multidisciplinary Expert Working Group
por: Marglani, Osama, et al.
Publicado: (2023)

The efficacy and safety of several interventions of corticosteroids for CRSwNP patients after endoscope sinus surgery: A protocol for systematic review and network meta-analysis
por: Zhang, Lan, et al.
Publicado: (2022)

P123 Study of naïve and memory T helper cell response in patients of chronic rhinosinusitis with nasal polyposis (CRSwNP) after in vitro exposure to Aspergillus flavus
por: Das, Shukla, et al.
Publicado: (2022)

Spotlight on a Short-Time Treatment with the IL-4/IL-13 Receptor Blocker in Patients with CRSwNP: microRNAs Modulations and Preliminary Clinical Evidence
por: Mimmi, Selena, et al.
Publicado: (2022)

Expression of Apoptosis-Related Biomarkers in Inflamed Nasal Sinus Epithelium of Patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP)—Evaluation at mRNA and miRNA Levels
por: Morawska-Kochman, Monika, et al.
Publicado: (2022)

The SMYD3-dependent H3K4me3 status of IGF2 intensifies local Th2 differentiation in CRSwNP via positive feedback
por: Yu, Lei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_17fijrgdovfbouqmct3hk1odv2