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Molecular dynamics and structure-based virtual screening and identification of natural compounds as Wnt signaling modulators: possible therapeutics for Alzheimer’s disease

Wnt signaling pathway is an evolutionarily conserved pathway responsible for neurogenesis, axon outgrowth, neuronal polarity, synapse formation, and maintenance. Downregulation of Wnt signaling has been found in patients with Alzheimer’s disease (AD). Several experimental approaches to activate Wnt...

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Detalles Bibliográficos
Autores principales:	Manandhar, Suman, Sankhe, Runali, Priya, Keerthi, Hari, Gangadhar, Kumar B., Harish, Mehta, Chetan H., Nayak, Usha Y., Pai, K. Sreedhara Ranganath
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532339/ https://www.ncbi.nlm.nih.gov/pubmed/35146638 http://dx.doi.org/10.1007/s11030-022-10395-8

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