Single-cell sequencing resolves the landscape of immune cells and regulatory mechanisms in HIV-infected immune non-responders

Immune non-responder after highly active antiretroviral therapy (HAART) is the main cause of opportunistic infections and high mortality in AIDS patients, but the mechanism underlying immune reconstitution failure is poorly understood. Here, we performed scRNA-seq, and scATAC-seq analysis of periphe...

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Detalles Bibliográficos
Autores principales: Li, Haiyu, Tang, Yongyao, Wang, Yujing, Li, Yue, Yang, Yi, Liao, Kui, Song, Fangzhou, Deng, Shixiong, Chen, Yaokai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532384/
https://www.ncbi.nlm.nih.gov/pubmed/36195585
http://dx.doi.org/10.1038/s41419-022-05225-6

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