Decoding the spatial chromatin organization and dynamic epigenetic landscapes of macrophage cells during differentiation and immune activation

Immunocytes dynamically reprogram their gene expression profiles during differentiation and immunoresponse. However, the underlying mechanism remains elusive. Here, we develop a single-cell Hi-C method and systematically delineate the 3D genome and dynamic epigenetic atlas of macrophages during thes...

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Detalles Bibliográficos
Autores principales: Lin, Da, Xu, Weize, Hong, Ping, Wu, Chengchao, Zhang, Zhihui, Zhang, Siheng, Xing, Lingyu, Yang, Bing, Zhou, Wei, Xiao, Qin, Wang, Jinyue, Wang, Cong, He, Yu, Chen, Xi, Cao, Xiaojian, Man, Jiangwei, Reheman, Aikebaier, Wu, Xiaofeng, Hao, Xingjie, Hu, Zhe, Chen, Chunli, Cao, Zimeng, Yin, Rong, Fu, Zhen F., Zhou, Rong, Teng, Zhaowei, Li, Guoliang, Cao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532393/
https://www.ncbi.nlm.nih.gov/pubmed/36195603
http://dx.doi.org/10.1038/s41467-022-33558-5

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