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Oxytocin and orexin systems bidirectionally regulate the ability of opioid cues to bias reward seeking

As opioid-related fatalities continue to rise, the need for novel opioid use disorder (OUD) treatments could not be more urgent. Two separate hypothalamic neuropeptide systems have shown promise in preclinical OUD models. The oxytocin system, originating in the paraventricular nucleus (PVN), may pro...

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Detalles Bibliográficos
Autores principales:	Giannotti, Giuseppe, Mottarlini, Francesca, Heinsbroek, Jasper A., Mandel, Mitchel R., James, Morgan H., Peters, Jamie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532415/ https://www.ncbi.nlm.nih.gov/pubmed/36195606 http://dx.doi.org/10.1038/s41398-022-02161-z

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