Multicellular immune dynamics implicate PIM1 as a potential therapeutic target for uveitis

Uveitis is a severe autoimmune disease, and a common cause of blindness; however, its individual cellular dynamics and pathogenic mechanism remain poorly understood. Herein, by performing single-cell RNA sequencing (scRNA-seq) on experimental autoimmune uveitis (EAU), we identify disease-associated...

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Detalles Bibliográficos
Autores principales: Li, He, Xie, Lihui, Zhu, Lei, Li, Zhaohuai, Wang, Rong, Liu, Xiuxing, Huang, Zhaohao, Chen, Binyao, Gao, Yuehan, Wei, Lai, He, Chang, Ju, Rong, Liu, Yizhi, Liu, Xialin, Zheng, Yingfeng, Su, Wenru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532430/
https://www.ncbi.nlm.nih.gov/pubmed/36195600
http://dx.doi.org/10.1038/s41467-022-33502-7

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