Needle-free, spirulina-produced Plasmodium falciparum circumsporozoite vaccination provides sterile protection against pre-erythrocytic malaria in mice

Antibodies against the Plasmodium falciparum circumsporozoite protein (PfCSP) can block hepatocyte infection by sporozoites and protect against malaria. Needle-free vaccination strategies are desirable, yet most PfCSP-targeted vaccines like RTS,S require needle-based administration. Here, we evaluat...

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Detalles Bibliográficos
Autores principales: Saveria, Tracy, Parthiban, Chaitra, Seilie, Annette M., Brady, Colin, Martinez, Anissa, Manocha, Ridhima, Afreen, Esha, Zhao, Hui, Krzeszowski, Ashley, Ferrara, Jeremy, Paddock, Troy, Roberts, James, Stone, Brad C., Tasch, Michael, Murphy, Sean C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532447/
https://www.ncbi.nlm.nih.gov/pubmed/36195607
http://dx.doi.org/10.1038/s41541-022-00534-5

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