Cargando…

Development of a novel knockout model of retinitis pigmentosa using Pde6b-knockout Long–Evans rats

Although rats with melanin-pigmentated retinal pigment epithelial (RPE) cells are physiologically more appropriate models for human eye research than their albino counterparts, reliable models from the former strain are not available to study retinal degeneration. Here, we describe the development o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Jee Myung, Kim, Bora, Kwak, Jiehoon, Lee, Min Kyung, Kim, Jeong Hoon, Baek, In-Jeoung, Sung, Young Hoon, Lee, Joo Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532504/ https://www.ncbi.nlm.nih.gov/pubmed/36213678 http://dx.doi.org/10.3389/fmed.2022.909182

Ejemplares similares

Long-term effects of human induced pluripotent stem cell-derived retinal cell transplantation in Pde6b knockout rats
por: Yang, Jee Myung, et al.
Publicado: (2021)

Clinical Phenotype of PDE6B-Associated Retinitis Pigmentosa
por: Kuehlewein, Laura, et al.
Publicado: (2021)

Knockout rat models mimicking human atherosclerosis created by Cpf1-mediated gene targeting
por: Lee, Jong Geol, et al.
Publicado: (2019)

Clinical characteristics and disease progression of retinitis pigmentosa associated with PDE6B mutations in Korean patients
por: Kim, You Na, et al.
Publicado: (2020)

Tsc2 knockout counteracts ubiquitin-proteasome system insufficiency and delays photoreceptor loss in retinitis pigmentosa
por: Wang, Yixiao, et al.
Publicado: (2022)

Novel PDE6A mutation in an Emirati patient with retinitis pigmentosa
por: Nair, Pratibha, et al.
Publicado: (2017)

Knockout of Ca(V)1.3 L-type calcium channels in a mouse model of retinitis pigmentosa
por: Kilicarslan, Irem, et al.
Publicado: (2021)

CCN5 knockout mice exhibit lipotoxic cardiomyopathy with mild obesity and diabetes
por: Kim, Jihwa, et al.
Publicado: (2018)

Establishment of the reproducible branch retinal artery occlusion mouse model and intravital longitudinal imaging of the retinal CX3CR1-GFP(+) cells after spontaneous arterial recanalization
por: Jeon, Jehwi, et al.
Publicado: (2022)

Novel variants in PDE6A and PDE6B genes and its phenotypes in patients with retinitis pigmentosa in Chinese families
por: Li, Yuyu, et al.
Publicado: (2022)

Gene Therapy in a Large Animal Model of PDE6A-Retinitis Pigmentosa
por: Mowat, Freya M., et al.
Publicado: (2017)

A New Preclinical Model of Retinitis Pigmentosa Due to Pde6g Deficiency
por: Jentzsch, Michelle Carmen, et al.
Publicado: (2023)

Clinical and genetic features of Koreans with retinitis pigmentosa associated with mutations in rhodopsin
por: Jung, Young Hoon, et al.
Publicado: (2023)

Spectrum of rhodopsin mutations in Korean patients with retinitis pigmentosa
por: Kim, Kwang Joong, et al.
Publicado: (2011)

Universal statistics of the knockout tournament
por: Baek, Seung Ki, et al.
Publicado: (2013)

Central Visual Function and Genotype–Phenotype Correlations in PDE6A-Associated Retinitis Pigmentosa
por: Kuehlewein, Laura, et al.
Publicado: (2022)

Changes in Glycogen and Glycosaminoglycan Levels in Hepatocytes of Iduronate-2-Sulfatase Knockout Mice before and after Recombinant Iduronate-2-Sulfatase Supplementation
por: Lee, Jee Hyun, et al.
Publicado: (2011)

Vascular defects of DYRK1A knockouts are ameliorated by modulating calcium signaling in zebrafish
por: Cho, Hyun-Ju, et al.
Publicado: (2019)

Collagen-Induced Arthritis Analysis in Rhbdf2 Knockout Mouse
por: Lee, Min-Young, et al.
Publicado: (2018)

Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases
por: Sung, Young Hoon, et al.
Publicado: (2014)

Splice-site mutations identified in PDE6A responsible for retinitis pigmentosa in consanguineous Pakistani families
por: Khan, Shahid Y., et al.
Publicado: (2015)

SNRNP200 Mutations Cause Autosomal Dominant Retinitis Pigmentosa
por: Zhang, Tao, et al.
Publicado: (2021)

Relationship Between Tamsulosin Use and Surgical Complications of Cataract Surgery in Elderly Patients: Population-Based Cohort Study
por: Kwak, Jiehoon, et al.
Publicado: (2022)

The Anti-Atherosclerosis Effect of Anakinra, a Recombinant Human Interleukin-1 Receptor Antagonist, in Apolipoprotein E Knockout Mice
por: Ku, Eu Jeong, et al.
Publicado: (2022)

Microarray-based mutation detection and phenotypic characterization in Korean patients with retinitis pigmentosa
por: Kim, Cinoo, et al.
Publicado: (2012)

CRISPR/Cas9-mediated generation of a Plac8 knockout mouse model
por: Lee, HyunJeong, et al.
Publicado: (2018)

Fatty Liver and Insulin Resistance in the Liver-Specific Knockout Mice of Mitogen Inducible Gene-6
por: Park, Byung Kil, et al.
Publicado: (2016)

Retinal Development and Pathophysiology in Kcnj13 Knockout Mice
por: Jiao, Xiaodong, et al.
Publicado: (2022)

Genome-edited HEADING DATE 3a knockout enhances leaf production in Perilla frutescens
por: Yun, Hee Rang, et al.
Publicado: (2023)

Retinitis Pigmentosa Associated with Bardet-Biedl Syndrome with BBS9 Gene Mutation in a Korean Patient
por: Kim, Yong Hoon, et al.
Publicado: (2020)

Carnosic acid slows photoreceptor degeneration in the Pde6b(rd10) mouse model of retinitis pigmentosa
por: Kang, Kai, et al.
Publicado: (2016)

Allele-Specific Knockout by CRISPR/Cas to Treat Autosomal Dominant Retinitis Pigmentosa Caused by the G56R Mutation in NR2E3
por: Diakatou, Michalitsa, et al.
Publicado: (2021)

CRISPR/Cas9-induced knockout and knock-in mutations in Chlamydomonas reinhardtii
por: Shin, Sung-Eun, et al.
Publicado: (2016)

Detection of Retinitis Pigmentosa by Differential Interference Contrast Microscopy
por: Oh, Juyeong, et al.
Publicado: (2014)

Mountain-cultivated ginseng protects against cognitive impairments in aged GPx-1 knockout mice via activation of Nrf2/ChAT/ERK signaling pathway
por: Nguyen, Bao Trong, et al.
Publicado: (2023)

Case Report: A Case of Cystoid Macular Edema in Retinitis Pigmentosa With Central Retinal Vein Occlusion
por: Wang, Da-Hu, et al.
Publicado: (2022)

CRISPR/Cas9-mediated knockout of Rag-2 causes systemic lymphopenia with hypoplastic lymphoid organs in FVB mice
por: Kim, Joo-Il, et al.
Publicado: (2018)

Production of Apolipoprotein C-III Knockout Rabbits using Zinc Finger Nucleases
por: Yang, Dongshan, et al.
Publicado: (2013)

AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa
por: Xue, Yunlu, et al.
Publicado: (2021)

Case Report: The First Reported Concurrence of Wilson Disease and Bilateral Retinitis Pigmentosa
por: Ye, Zifan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_sger73vfcqdjevdgdjem5vsr0f