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Ionic co-aggregates (ICAs) based oral drug delivery: Solubilization and permeability improvement
Due to the overwhelming percentage of poorly water-soluble drugs, pharmaceutical industry is in urgent need of efficient approaches for solubilization and permeability improvement. Salts consisting of lipophilic fatty acid anions and hydrophilic choline cations are found to be surface active and abl...
Autores principales: | Zheng, Xianzi, Fang, Zhezheng, Huang, Weizi, Qi, Jianping, Dong, Xiaochun, Zhao, Weili, Wu, Wei, Lu, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532535/ https://www.ncbi.nlm.nih.gov/pubmed/36213530 http://dx.doi.org/10.1016/j.apsb.2022.04.011 |
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