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Macrophage-mediated tumor-targeted delivery of engineered Salmonella typhimurium VNP20009 in anti-PD1 therapy against melanoma

Bacterial antitumor therapy has great application potential given its unique characteristics, including genetic manipulation, tumor targeting specificity and immune system modulation. However, the nonnegligible side effects and limited efficacy of clinical treatment limit their biomedical applicatio...

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Detalles Bibliográficos
Autores principales: Wu, Leyang, Li, Lin, Li, Shufeng, Liu, Lina, Xin, Wenjie, Li, Chenyang, Yin, Xingpeng, Xu, Xuebo, Bao, Feifei, Hua, Zichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532557/
https://www.ncbi.nlm.nih.gov/pubmed/36213533
http://dx.doi.org/10.1016/j.apsb.2022.05.006