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Risk factors, types, and neuroimaging findings in Children with Cerebral Palsy

OBJECTIVES: Cerebral palsy is a major cause of neurodisability in children in Pakistan. The study aims to evaluate the risk factors, types and neuroimaging findings in children with cerebral palsy. METHODS: All children diagnosed with cerebral palsy, between 1-16 years presenting to Shifa community...

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Autores principales: Khan, Sabeen Abid, Talat, Sidra, Malik, Munir Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Professional Medical Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532638/
https://www.ncbi.nlm.nih.gov/pubmed/36246690
http://dx.doi.org/10.12669/pjms.38.7.6175
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author Khan, Sabeen Abid
Talat, Sidra
Malik, Munir Iqbal
author_facet Khan, Sabeen Abid
Talat, Sidra
Malik, Munir Iqbal
author_sort Khan, Sabeen Abid
collection PubMed
description OBJECTIVES: Cerebral palsy is a major cause of neurodisability in children in Pakistan. The study aims to evaluate the risk factors, types and neuroimaging findings in children with cerebral palsy. METHODS: All children diagnosed with cerebral palsy, between 1-16 years presenting to Shifa community health center were enrolled from January 2020 to July 2021. Informed consent was taken from parents. RESULTS: A total of 89 patients were included, 62 (69.7%) male and 27 (30.3%) females. Mean age was 4.4 ± 2.8 years. Majority of babies were born at term 74 (84%) and 15 were preterm (16%). Most of the patients were born in hospital 55 (62%), 13 (14%) were born at home. Mean birth weight was 2.3 ± 0.3. Consanguinity was present in 56 (62.9%). Birth asphyxia 38 (42.7%) was the most common cause of cerebral palsy. Maternal antenatal risk factors identified were anemia 13 (14.6%), PIH (9%) infections (6%) were significant risk factors (<0.05). Neuroimaging was done in 37 (38.7%) of the patients only. CONCLUSION: Male gender is more affected in our cohort. Maternal anemia, pregnancy induced hypertension and low birth weight are significant modifiable risk factors. Prevention of these can reduce the incidence of cerebral palsy.
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spelling pubmed-95326382022-10-14 Risk factors, types, and neuroimaging findings in Children with Cerebral Palsy Khan, Sabeen Abid Talat, Sidra Malik, Munir Iqbal Pak J Med Sci Original Article OBJECTIVES: Cerebral palsy is a major cause of neurodisability in children in Pakistan. The study aims to evaluate the risk factors, types and neuroimaging findings in children with cerebral palsy. METHODS: All children diagnosed with cerebral palsy, between 1-16 years presenting to Shifa community health center were enrolled from January 2020 to July 2021. Informed consent was taken from parents. RESULTS: A total of 89 patients were included, 62 (69.7%) male and 27 (30.3%) females. Mean age was 4.4 ± 2.8 years. Majority of babies were born at term 74 (84%) and 15 were preterm (16%). Most of the patients were born in hospital 55 (62%), 13 (14%) were born at home. Mean birth weight was 2.3 ± 0.3. Consanguinity was present in 56 (62.9%). Birth asphyxia 38 (42.7%) was the most common cause of cerebral palsy. Maternal antenatal risk factors identified were anemia 13 (14.6%), PIH (9%) infections (6%) were significant risk factors (<0.05). Neuroimaging was done in 37 (38.7%) of the patients only. CONCLUSION: Male gender is more affected in our cohort. Maternal anemia, pregnancy induced hypertension and low birth weight are significant modifiable risk factors. Prevention of these can reduce the incidence of cerebral palsy. Professional Medical Publications 2022 /pmc/articles/PMC9532638/ /pubmed/36246690 http://dx.doi.org/10.12669/pjms.38.7.6175 Text en Copyright: © Pakistan Journal of Medical Sciences https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0 (https://creativecommons.org/licenses/by/3.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Khan, Sabeen Abid
Talat, Sidra
Malik, Munir Iqbal
Risk factors, types, and neuroimaging findings in Children with Cerebral Palsy
title Risk factors, types, and neuroimaging findings in Children with Cerebral Palsy
title_full Risk factors, types, and neuroimaging findings in Children with Cerebral Palsy
title_fullStr Risk factors, types, and neuroimaging findings in Children with Cerebral Palsy
title_full_unstemmed Risk factors, types, and neuroimaging findings in Children with Cerebral Palsy
title_short Risk factors, types, and neuroimaging findings in Children with Cerebral Palsy
title_sort risk factors, types, and neuroimaging findings in children with cerebral palsy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532638/
https://www.ncbi.nlm.nih.gov/pubmed/36246690
http://dx.doi.org/10.12669/pjms.38.7.6175
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