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The relationship between choroidal thickness and axis length and corneal curvature in high myopia

OBJECTIVES: To measure choroidal thickness (CT) in highly myopia eyes using enhanced depth imaging spectral-domain optical tomography (EDI SD-OCT) and explore the relationship between the CT and axial length (AL) and corneal curvature. METHODS: This study assessed 66 eyes of 33 patients with both ey...

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Autores principales: Lu, Hongwei, Guan, Yongqing, Wei, Guangchuan, Li, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Professional Medical Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532658/
https://www.ncbi.nlm.nih.gov/pubmed/36246672
http://dx.doi.org/10.12669/pjms.38.7.6409
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author Lu, Hongwei
Guan, Yongqing
Wei, Guangchuan
Li, Na
author_facet Lu, Hongwei
Guan, Yongqing
Wei, Guangchuan
Li, Na
author_sort Lu, Hongwei
collection PubMed
description OBJECTIVES: To measure choroidal thickness (CT) in highly myopia eyes using enhanced depth imaging spectral-domain optical tomography (EDI SD-OCT) and explore the relationship between the CT and axial length (AL) and corneal curvature. METHODS: This study assessed 66 eyes of 33 patients with both eyes of high myopia (equivalent sphericity ≥-6D or AL≥26mm) who underwent treatment at the department of ophthalmology, fourth hospital of Hebei Medical University from August 2020 to August 2021(High-myopia group). The control group included 54 eyes from 27 healthy volunteers. The patients in the two groups were 18~40 years old. EDI SD-OCT was used to measure the CT of subfoveal choroidal thickness (SFCT) and CT from fovea to nasal and temporal sides at an interval of 500~2500μm. The intraocular pressure, diopter, ocular axis, corneal curvature, and CT were compared between the two groups. The correlation between CT, diopter and AL was measured by Pearson’s r. RESULTS: The diopter, AL, vertical corneal curvature, and CT in the high-myopia group were significantly higher than those in the control group (P<0.05). There was significant correlation between SFCT and AL in both groups (P<0.05). There was a negative correlation between AL and CT in high-myopia group (r=-0.395, P<0.05), and a positive correlation between AL and CT in control group (r=0.29, P<0.05). There was a weak correlation between AL and gender, intraocular pressure, and horizontal corneal curvature(P<0.05), and a negative correlation between AL and diopter (r=-0.861, P<0.001). CONCLUSION: EDI SD-OCT can quantitatively measure the CT of high myopia. The CT of patients with high myopia was significantly thinner than that of the control group of the same age. There was a significant correlation between diopter, AL and CT, suggesting that AL is a parameter indicating the degree of myopia, and the change of CT may play a role in the occurrence and development of high myopia.
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spelling pubmed-95326582022-10-14 The relationship between choroidal thickness and axis length and corneal curvature in high myopia Lu, Hongwei Guan, Yongqing Wei, Guangchuan Li, Na Pak J Med Sci Original Article OBJECTIVES: To measure choroidal thickness (CT) in highly myopia eyes using enhanced depth imaging spectral-domain optical tomography (EDI SD-OCT) and explore the relationship between the CT and axial length (AL) and corneal curvature. METHODS: This study assessed 66 eyes of 33 patients with both eyes of high myopia (equivalent sphericity ≥-6D or AL≥26mm) who underwent treatment at the department of ophthalmology, fourth hospital of Hebei Medical University from August 2020 to August 2021(High-myopia group). The control group included 54 eyes from 27 healthy volunteers. The patients in the two groups were 18~40 years old. EDI SD-OCT was used to measure the CT of subfoveal choroidal thickness (SFCT) and CT from fovea to nasal and temporal sides at an interval of 500~2500μm. The intraocular pressure, diopter, ocular axis, corneal curvature, and CT were compared between the two groups. The correlation between CT, diopter and AL was measured by Pearson’s r. RESULTS: The diopter, AL, vertical corneal curvature, and CT in the high-myopia group were significantly higher than those in the control group (P<0.05). There was significant correlation between SFCT and AL in both groups (P<0.05). There was a negative correlation between AL and CT in high-myopia group (r=-0.395, P<0.05), and a positive correlation between AL and CT in control group (r=0.29, P<0.05). There was a weak correlation between AL and gender, intraocular pressure, and horizontal corneal curvature(P<0.05), and a negative correlation between AL and diopter (r=-0.861, P<0.001). CONCLUSION: EDI SD-OCT can quantitatively measure the CT of high myopia. The CT of patients with high myopia was significantly thinner than that of the control group of the same age. There was a significant correlation between diopter, AL and CT, suggesting that AL is a parameter indicating the degree of myopia, and the change of CT may play a role in the occurrence and development of high myopia. Professional Medical Publications 2022 /pmc/articles/PMC9532658/ /pubmed/36246672 http://dx.doi.org/10.12669/pjms.38.7.6409 Text en Copyright: © Pakistan Journal of Medical Sciences https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0 (https://creativecommons.org/licenses/by/3.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lu, Hongwei
Guan, Yongqing
Wei, Guangchuan
Li, Na
The relationship between choroidal thickness and axis length and corneal curvature in high myopia
title The relationship between choroidal thickness and axis length and corneal curvature in high myopia
title_full The relationship between choroidal thickness and axis length and corneal curvature in high myopia
title_fullStr The relationship between choroidal thickness and axis length and corneal curvature in high myopia
title_full_unstemmed The relationship between choroidal thickness and axis length and corneal curvature in high myopia
title_short The relationship between choroidal thickness and axis length and corneal curvature in high myopia
title_sort relationship between choroidal thickness and axis length and corneal curvature in high myopia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532658/
https://www.ncbi.nlm.nih.gov/pubmed/36246672
http://dx.doi.org/10.12669/pjms.38.7.6409
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