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A novel small molecule RK-019 inhibits FGFR2-amplification gastric cancer cell proliferation and induces apoptosis in vitro and in vivo

Gastric cancer (GC) is one of the most malignant cancers and is estimated to be fifth in incidence ratio and the third leading cause of cancer death worldwide. Despite advances in GC treatment, poor prognosis and low survival rate necessitate the development of novel treatment options. Fibroblast gr...

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Detalles Bibliográficos
Autores principales: Zeng, Jun, Ran, Kai, Li, Xinyue, Tao, Longyue, Wang, Qiwei, Ren, Jiangtao, Hu, Rong, Zhu, Yongxia, Liu, Zhihao, Yu, Luoting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532703/
https://www.ncbi.nlm.nih.gov/pubmed/36210834
http://dx.doi.org/10.3389/fphar.2022.998199