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Autologous humanized mouse models to study combination and single-agent immunotherapy for colorectal cancer patient-derived xenografts

Designing studies of immunotherapy is limited due to a lack of pre-clinical models that reliably predict effective immunotherapy responses. To address this gap, we developed humanized mouse models of colorectal cancer (CRC) incorporating patient-derived xenografts (PDX) with human peripheral blood m...

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Detalles Bibliográficos
Autores principales:	Kanikarla Marie, Preeti, Sorokin, Alexey V., Bitner, Lea A., Aden, Rebecca, Lam, Michael, Manyam, Ganiraju, Woods, Melanie N., Anderson, Amanda, Capasso, Anna, Fowlkes, Natalie, Overman, Michael J., Menter, David G., Kopetz, Scott
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532947/ https://www.ncbi.nlm.nih.gov/pubmed/36212401 http://dx.doi.org/10.3389/fonc.2022.994333

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