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The controversy of klotho as a potential biomarker in chronic kidney disease

Klotho is an identified longevity gene with beneficial pleiotropic effects on the kidney. Evidence shows that a decline in serum Klotho level occurs in early chronic kidney disease (CKD) and continues as CKD progresses. Klotho deficiency is associated with poor clinical outcomes and CKD mineral bone...

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Detalles Bibliográficos
Autores principales: Yu, Li-Xia, Li, Sha-Sha, Sha, Min-Yue, Kong, Jia-Wei, Ye, Jian-Ming, Liu, Qi-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9532967/
https://www.ncbi.nlm.nih.gov/pubmed/36210812
http://dx.doi.org/10.3389/fphar.2022.931746