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An integrated RNA sequencing and network pharmacology approach reveals the molecular mechanism of dapagliflozin in the treatment of diabetic nephropathy

Dapagliflozin, an inhibitor of sodium-glucose cotransporter 2 (SGLT2), is a new type of oral hypoglycemic drugs which can promote glucose excretion in the kidney. Studies have shown that dapagliflozin has renoprotective effect in the treatment of type 2 diabetes. However, the underlying mechanism re...

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Detalles Bibliográficos
Autores principales:	Bai, Zhenyu, Xie, Ting, Liu, Tianhao, Chen, Zedong, Yu, Linde, Zhang, Chao, Luo, Jincheng, Chen, Liguo, Zhao, Xiaoshan, Xiao, Ya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533015/ https://www.ncbi.nlm.nih.gov/pubmed/36213291 http://dx.doi.org/10.3389/fendo.2022.967822

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