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Hyperglycemia‐mediated oocyte TET3 insufficiency predisposes offspring to glucose intolerance

In a recent article published in Nature, Chen et al. reported that pregestational hyperglycemia rendered offspring vulnerable to glucose intolerance due to insufficient TET3‐mediated 5‐methylcytosine oxidation and DNA demethylation, resulting in hypermethylation and reduction of insulin‐secreting ge...

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Detalles Bibliográficos
Autores principales:	Wu, Xiumei, Xu, Suowen, Weng, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533033/ https://www.ncbi.nlm.nih.gov/pubmed/35839128 http://dx.doi.org/10.1111/jdi.13885

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