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Association of ideal cardiovascular health metrics and incident type 2 diabetes mellitus among an urban population of Iran: One decade follow up in the Tehran Lipid and Glucose Study

AIMS/INTRODUCTION: To evaluate the association between ideal cardiovascular health metrics (ICVHM) and incident type 2 diabetes mellitus among Iranian men and women. MATERIALS AND METHODS: The study population included 7,488 Iranian adults aged ≥20 years (4,236 women) free from diabetes at baseline....

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Autores principales: Asgari, Samaneh, Masrouri, Soroush, Hosseinpour‐Niazi, Somaye, Moslehi, Nazanin, Azizi, Fereidoun, Hadaegh, Farzad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533049/
https://www.ncbi.nlm.nih.gov/pubmed/35588067
http://dx.doi.org/10.1111/jdi.13839
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author Asgari, Samaneh
Masrouri, Soroush
Hosseinpour‐Niazi, Somaye
Moslehi, Nazanin
Azizi, Fereidoun
Hadaegh, Farzad
author_facet Asgari, Samaneh
Masrouri, Soroush
Hosseinpour‐Niazi, Somaye
Moslehi, Nazanin
Azizi, Fereidoun
Hadaegh, Farzad
author_sort Asgari, Samaneh
collection PubMed
description AIMS/INTRODUCTION: To evaluate the association between ideal cardiovascular health metrics (ICVHM) and incident type 2 diabetes mellitus among Iranian men and women. MATERIALS AND METHODS: The study population included 7,488 Iranian adults aged ≥20 years (4,236 women) free from diabetes at baseline. The ICVHM was defined according to the American Heart Association's 2020 impact goals. The multivariable Cox proportional hazards regression analysis was used to calculate the hazard ratios (HRs) for ICVHM both as continuous and categorical variables. RESULTS: Over the median of 9.1 years of follow‐up, we identified 922 new cases of type 2 diabetes mellitus (526 women). Body mass index <30 kg/m(2), untreated systolic/diastolic blood pressure <120/80 mmHg in both sexes, and physical activity ≥1,500 MET min/week (only among men) were significantly associated with a lower risk of type 2 diabetes mellitus. Each additional unit in the ICVHM was associated with a 21 and 15% lower risk of type 2 diabetes mellitus in men and women, respectively (P‐values <0.05). Compared with participants having poor cardiovascular health, the HR for type 2 diabetes mellitus risk was 0.69 (95% confidence interval [CI] 0.56–0.85) and 0.35 (95% CI 0.21–0.59) for men with intermediate and ideal CVHM, respectively. The corresponding values for women were 0.79 (95% CI 0.65–0.97) and 0.30 (95% CI 0.15–0.60), respectively. In a subpopulation with nutritional data (n = 2,236), ideal and intermediate nutritional status was associated with 83 and 77% lower risk of type 2 diabetes mellitus only among women (P‐values <0.05). CONCLUSION: We found a strong inverse association between having higher global ICVHM with incident type 2 diabetes mellitus; which is mainly attributable to normal blood pressure, normal body weight, and intensive physical activity (only for men).
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spelling pubmed-95330492022-10-11 Association of ideal cardiovascular health metrics and incident type 2 diabetes mellitus among an urban population of Iran: One decade follow up in the Tehran Lipid and Glucose Study Asgari, Samaneh Masrouri, Soroush Hosseinpour‐Niazi, Somaye Moslehi, Nazanin Azizi, Fereidoun Hadaegh, Farzad J Diabetes Investig Articles AIMS/INTRODUCTION: To evaluate the association between ideal cardiovascular health metrics (ICVHM) and incident type 2 diabetes mellitus among Iranian men and women. MATERIALS AND METHODS: The study population included 7,488 Iranian adults aged ≥20 years (4,236 women) free from diabetes at baseline. The ICVHM was defined according to the American Heart Association's 2020 impact goals. The multivariable Cox proportional hazards regression analysis was used to calculate the hazard ratios (HRs) for ICVHM both as continuous and categorical variables. RESULTS: Over the median of 9.1 years of follow‐up, we identified 922 new cases of type 2 diabetes mellitus (526 women). Body mass index <30 kg/m(2), untreated systolic/diastolic blood pressure <120/80 mmHg in both sexes, and physical activity ≥1,500 MET min/week (only among men) were significantly associated with a lower risk of type 2 diabetes mellitus. Each additional unit in the ICVHM was associated with a 21 and 15% lower risk of type 2 diabetes mellitus in men and women, respectively (P‐values <0.05). Compared with participants having poor cardiovascular health, the HR for type 2 diabetes mellitus risk was 0.69 (95% confidence interval [CI] 0.56–0.85) and 0.35 (95% CI 0.21–0.59) for men with intermediate and ideal CVHM, respectively. The corresponding values for women were 0.79 (95% CI 0.65–0.97) and 0.30 (95% CI 0.15–0.60), respectively. In a subpopulation with nutritional data (n = 2,236), ideal and intermediate nutritional status was associated with 83 and 77% lower risk of type 2 diabetes mellitus only among women (P‐values <0.05). CONCLUSION: We found a strong inverse association between having higher global ICVHM with incident type 2 diabetes mellitus; which is mainly attributable to normal blood pressure, normal body weight, and intensive physical activity (only for men). John Wiley and Sons Inc. 2022-06-20 2022-10 /pmc/articles/PMC9533049/ /pubmed/35588067 http://dx.doi.org/10.1111/jdi.13839 Text en © 2022 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Articles
Asgari, Samaneh
Masrouri, Soroush
Hosseinpour‐Niazi, Somaye
Moslehi, Nazanin
Azizi, Fereidoun
Hadaegh, Farzad
Association of ideal cardiovascular health metrics and incident type 2 diabetes mellitus among an urban population of Iran: One decade follow up in the Tehran Lipid and Glucose Study
title Association of ideal cardiovascular health metrics and incident type 2 diabetes mellitus among an urban population of Iran: One decade follow up in the Tehran Lipid and Glucose Study
title_full Association of ideal cardiovascular health metrics and incident type 2 diabetes mellitus among an urban population of Iran: One decade follow up in the Tehran Lipid and Glucose Study
title_fullStr Association of ideal cardiovascular health metrics and incident type 2 diabetes mellitus among an urban population of Iran: One decade follow up in the Tehran Lipid and Glucose Study
title_full_unstemmed Association of ideal cardiovascular health metrics and incident type 2 diabetes mellitus among an urban population of Iran: One decade follow up in the Tehran Lipid and Glucose Study
title_short Association of ideal cardiovascular health metrics and incident type 2 diabetes mellitus among an urban population of Iran: One decade follow up in the Tehran Lipid and Glucose Study
title_sort association of ideal cardiovascular health metrics and incident type 2 diabetes mellitus among an urban population of iran: one decade follow up in the tehran lipid and glucose study
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533049/
https://www.ncbi.nlm.nih.gov/pubmed/35588067
http://dx.doi.org/10.1111/jdi.13839
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