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Randomized placebo-controlled double-blind phase II study of zaltoprofen for patients with diffuse-type and unresectable localized tenosynovial giant cell tumors: The REALIZE study

BACKGROUND: A tenosynovial giant cell tumor (TGCT) is a locally aggressive benign neoplasm arising from intra- or extra-articular tissue, categorized as localized (L-TGCT, solitary lesion) and diffuse (D-TGCT, multiple lesions) TGCT. Surgical excision is the mainstay of the treatment, and a high loc...

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Detalles Bibliográficos
Autores principales: Takeuchi, Akihiko, Endo, Makoto, Kawai, Akira, Nishida, Yoshihiro, Terauchi, Ryu, Matsumine, Akihiko, Aiba, Hisaki, Nakamura, Tomoki, Tandai, Susumu, Ozaki, Toshifumi, Hoshi, Manabu, Kayano, Daiki, Okuda, Miho, Yamamoto, Norio, Hayashi, Katsuhiro, Miwa, Shinji, Igarashi, Kentaro, Yoshimura, Kenichi, Nomura, Akihiro, Murayama, Toshinori, Tsuchiya, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533097/
https://www.ncbi.nlm.nih.gov/pubmed/36212437
http://dx.doi.org/10.3389/fonc.2022.900010