Case report: Leukemia cutis as the first manifestation of chronic neutrophilic leukemia in a 6-year-old girl

Chronic neutrophilic leukemia (CNL) is a rare BCR-ABL negative myeloproliferative neoplasm that usually affects older adults with a poor prognosis. Leukemia cutis is an extramedullary manifestation of leukemia and may be misdiagnosed by dermatologists. Here, we describe a case of CNL in a 6-year-old...

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Autores principales: Zhou, Ya Bin, Yao, Jia Feng, Xu, Zi Gang, Wu, Rui Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533139/
https://www.ncbi.nlm.nih.gov/pubmed/36210951
http://dx.doi.org/10.3389/fped.2022.972224
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author Zhou, Ya Bin
Yao, Jia Feng
Xu, Zi Gang
Wu, Rui Hui
author_facet Zhou, Ya Bin
Yao, Jia Feng
Xu, Zi Gang
Wu, Rui Hui
author_sort Zhou, Ya Bin
collection PubMed
description Chronic neutrophilic leukemia (CNL) is a rare BCR-ABL negative myeloproliferative neoplasm that usually affects older adults with a poor prognosis. Leukemia cutis is an extramedullary manifestation of leukemia and may be misdiagnosed by dermatologists. Here, we describe a case of CNL in a 6-year-old Chinese girl with leukemia cutis as the first manifestation. Her skin rashes failed to attract the attention of dermatologists in early stages. The diagnosis was confirmed by peripheral smear, bone marrow studies, genomic analysis and skin biopsy.
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spelling pubmed-95331392022-10-06 Case report: Leukemia cutis as the first manifestation of chronic neutrophilic leukemia in a 6-year-old girl Zhou, Ya Bin Yao, Jia Feng Xu, Zi Gang Wu, Rui Hui Front Pediatr Pediatrics Chronic neutrophilic leukemia (CNL) is a rare BCR-ABL negative myeloproliferative neoplasm that usually affects older adults with a poor prognosis. Leukemia cutis is an extramedullary manifestation of leukemia and may be misdiagnosed by dermatologists. Here, we describe a case of CNL in a 6-year-old Chinese girl with leukemia cutis as the first manifestation. Her skin rashes failed to attract the attention of dermatologists in early stages. The diagnosis was confirmed by peripheral smear, bone marrow studies, genomic analysis and skin biopsy. Frontiers Media S.A. 2022-09-21 /pmc/articles/PMC9533139/ /pubmed/36210951 http://dx.doi.org/10.3389/fped.2022.972224 Text en Copyright © 2022 Zhou, Yao, Xu and Wu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Zhou, Ya Bin
Yao, Jia Feng
Xu, Zi Gang
Wu, Rui Hui
Case report: Leukemia cutis as the first manifestation of chronic neutrophilic leukemia in a 6-year-old girl
title Case report: Leukemia cutis as the first manifestation of chronic neutrophilic leukemia in a 6-year-old girl
title_full Case report: Leukemia cutis as the first manifestation of chronic neutrophilic leukemia in a 6-year-old girl
title_fullStr Case report: Leukemia cutis as the first manifestation of chronic neutrophilic leukemia in a 6-year-old girl
title_full_unstemmed Case report: Leukemia cutis as the first manifestation of chronic neutrophilic leukemia in a 6-year-old girl
title_short Case report: Leukemia cutis as the first manifestation of chronic neutrophilic leukemia in a 6-year-old girl
title_sort case report: leukemia cutis as the first manifestation of chronic neutrophilic leukemia in a 6-year-old girl
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533139/
https://www.ncbi.nlm.nih.gov/pubmed/36210951
http://dx.doi.org/10.3389/fped.2022.972224
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