Proline metabolism reprogramming of trained macrophages induced by early respiratory infection combined with allergen sensitization contributes to development of allergic asthma in childhood of mice

BACKGROUND: Infants with respiratory syncytial virus (RSV)-associated bronchiolitis are at increased risk of childhood asthma. Recent studies demonstrated that certain infections induce innate immune memory (also termed trained immunity), especially in macrophages, to respond more strongly to future...

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Detalles Bibliográficos
Autores principales: Li, Hanglin, Ma, Linyan, Li, Wenjian, Zheng, Boyang, Wang, Junhai, Chen, Shunyan, Wang, Yang, Ge, Fei, Qin, Beibei, Zheng, Xiaoqing, Deng, Yuqing, Zeng, Ruihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533174/
https://www.ncbi.nlm.nih.gov/pubmed/36211408
http://dx.doi.org/10.3389/fimmu.2022.977235

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