Septic arthritis in an in vivo murine model induced by Staphylococcus aureus : a comparison between actions of the haemolysin toxin and the effects of the host immune response

AIMS: Staphylococcus aureus is a major cause of septic arthritis, and in vitro studies suggest α haemolysin (Hla) is responsible for chondrocyte death. We used an in vivo murine joint model to compare inoculation with wild type S. aureus 8325-4 with a Hla-deficient strain DU1090 on chondrocyte viabi...

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Detalles Bibliográficos
Autores principales: Clement, Rhys G. E., Hall, Andrew C., Wong, Seng J., Howie, Sarah E. M., Simpson, A. Hamish R. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2022
Materias:
Arthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533245/
https://www.ncbi.nlm.nih.gov/pubmed/36066341
http://dx.doi.org/10.1302/2046-3758.119.BJR-2022-0016.R1

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