Quinoline derivatives volunteering against antimicrobial resistance: rational approaches, design strategies, structure activity relationship and mechanistic insights

Emergence of antimicrobial resistance has become a great threat to human species as there is shortage of development of new antimicrobial agents. So, its mandatary to combat AMR by initiating research and developing new novel antimicrobial agents. Among phytoconstituents, Quinoline (nitrogen contain...

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Detalles Bibliográficos
Autores principales: Kumar, Nitish, Khanna, Aanchal, Kaur, Komalpreet, Kaur, Harmandeep, Sharma, Anchal, Bedi, Preet Mohinder Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Comprehensive Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533295/
https://www.ncbi.nlm.nih.gov/pubmed/36197551
http://dx.doi.org/10.1007/s11030-022-10537-y
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author Kumar, Nitish
Khanna, Aanchal
Kaur, Komalpreet
Kaur, Harmandeep
Sharma, Anchal
Bedi, Preet Mohinder Singh
author_facet Kumar, Nitish
Khanna, Aanchal
Kaur, Komalpreet
Kaur, Harmandeep
Sharma, Anchal
Bedi, Preet Mohinder Singh
author_sort Kumar, Nitish
collection PubMed
description Emergence of antimicrobial resistance has become a great threat to human species as there is shortage of development of new antimicrobial agents. So, its mandatary to combat AMR by initiating research and developing new novel antimicrobial agents. Among phytoconstituents, Quinoline (nitrogen containing heterocyclic) have played a wide role in providing new bioactive molecules. So, this review provides rational approaches, design strategies, structure activity relationship and mechanistic insights of newly developed quinoline derivatives as antimicrobial agents. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-95332952022-10-05 Quinoline derivatives volunteering against antimicrobial resistance: rational approaches, design strategies, structure activity relationship and mechanistic insights Kumar, Nitish Khanna, Aanchal Kaur, Komalpreet Kaur, Harmandeep Sharma, Anchal Bedi, Preet Mohinder Singh Mol Divers Comprehensive Review Emergence of antimicrobial resistance has become a great threat to human species as there is shortage of development of new antimicrobial agents. So, its mandatary to combat AMR by initiating research and developing new novel antimicrobial agents. Among phytoconstituents, Quinoline (nitrogen containing heterocyclic) have played a wide role in providing new bioactive molecules. So, this review provides rational approaches, design strategies, structure activity relationship and mechanistic insights of newly developed quinoline derivatives as antimicrobial agents. GRAPHICAL ABSTRACT: [Image: see text] Springer International Publishing 2022-10-05 /pmc/articles/PMC9533295/ /pubmed/36197551 http://dx.doi.org/10.1007/s11030-022-10537-y Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Comprehensive Review
Kumar, Nitish
Khanna, Aanchal
Kaur, Komalpreet
Kaur, Harmandeep
Sharma, Anchal
Bedi, Preet Mohinder Singh
Quinoline derivatives volunteering against antimicrobial resistance: rational approaches, design strategies, structure activity relationship and mechanistic insights
title Quinoline derivatives volunteering against antimicrobial resistance: rational approaches, design strategies, structure activity relationship and mechanistic insights
title_full Quinoline derivatives volunteering against antimicrobial resistance: rational approaches, design strategies, structure activity relationship and mechanistic insights
title_fullStr Quinoline derivatives volunteering against antimicrobial resistance: rational approaches, design strategies, structure activity relationship and mechanistic insights
title_full_unstemmed Quinoline derivatives volunteering against antimicrobial resistance: rational approaches, design strategies, structure activity relationship and mechanistic insights
title_short Quinoline derivatives volunteering against antimicrobial resistance: rational approaches, design strategies, structure activity relationship and mechanistic insights
title_sort quinoline derivatives volunteering against antimicrobial resistance: rational approaches, design strategies, structure activity relationship and mechanistic insights
topic Comprehensive Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533295/
https://www.ncbi.nlm.nih.gov/pubmed/36197551
http://dx.doi.org/10.1007/s11030-022-10537-y
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