Evaluation of a PEGylated Fibroblast Growth Factor 21 Variant Using Novel Preclinical Magnetic Resonance Imaging and Magnetic Resonance Elastography in a Mouse Model of Nonalcoholic Steatohepatitis

BACKGROUND: Treatments for nonalcoholic steatohepatitis (NASH) are urgently needed. Hepatic fat fraction and shear stiffness quantified by magnetic resonance imaging (MRI‐HFF) and magnetic resonance elastography (MRE‐SS), respectively, are biomarkers for hepatic steatosis and fibrosis. PURPOSE: This...

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Detalles Bibliográficos
Autores principales: Tang, Haiying, Li, Jiahui, Zinker, Bradley, Boehm, Stephanie, Mauer, Amy, Rex‐Rabe, Sandra, Glaser, Kevin J., Fronheiser, Matthew, Bradstreet, Thomas, Nakao, Yasuhiko, Petrone, Thomas, Pena, Adrienne, Villano, MacKenzie, Chow, Patrick, Malhi, Harmeet, Charles, Edgar D., Hayes, Wendy, Ehman, Richard L., Du, Shuyan, Yin, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533307/
https://www.ncbi.nlm.nih.gov/pubmed/35092323
http://dx.doi.org/10.1002/jmri.28077

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