Mechanism of action of CTRP6 in the regulation of tumorigenesis in the digestive system

Tumors of the digestive system have always received attention, and their occurrence and development are regulated by various mechanisms such as inflammation and immunity, glucose and lipid metabolism, and tumor angiogenesis. Complement Clq/TNF-related protein 6 (CTRP6) is a member of the CTRP family...

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Autores principales: Zhang, Aimin, Kong, Mowei, Zhang, Xiuyun, Pei, Zhenying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533366/
https://www.ncbi.nlm.nih.gov/pubmed/36276484
http://dx.doi.org/10.3892/ol.2022.13511
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author Zhang, Aimin
Kong, Mowei
Zhang, Xiuyun
Pei, Zhenying
author_facet Zhang, Aimin
Kong, Mowei
Zhang, Xiuyun
Pei, Zhenying
author_sort Zhang, Aimin
collection PubMed
description Tumors of the digestive system have always received attention, and their occurrence and development are regulated by various mechanisms such as inflammation and immunity, glucose and lipid metabolism, and tumor angiogenesis. Complement Clq/TNF-related protein 6 (CTRP6) is a member of the CTRP family; it is widely expressed in various tissues and cell types, and plays a biological role in a number of mechanisms, such as glucose and lipid metabolism and inflammation. Recent studies have revealed the tumor-promoting effect of CTRP6 in gastric cancer, liver cancer, colorectal cancer and other gastrointestinal tumors, but, to the best of our knowledge, there has been no systematic discussion on the tumor-promoting mechanism of CTRP6. The present study reviews the role of CTRP6 in tumors of the digestive system and its possible mechanisms.
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spelling pubmed-95333662022-10-20 Mechanism of action of CTRP6 in the regulation of tumorigenesis in the digestive system Zhang, Aimin Kong, Mowei Zhang, Xiuyun Pei, Zhenying Oncol Lett Review Tumors of the digestive system have always received attention, and their occurrence and development are regulated by various mechanisms such as inflammation and immunity, glucose and lipid metabolism, and tumor angiogenesis. Complement Clq/TNF-related protein 6 (CTRP6) is a member of the CTRP family; it is widely expressed in various tissues and cell types, and plays a biological role in a number of mechanisms, such as glucose and lipid metabolism and inflammation. Recent studies have revealed the tumor-promoting effect of CTRP6 in gastric cancer, liver cancer, colorectal cancer and other gastrointestinal tumors, but, to the best of our knowledge, there has been no systematic discussion on the tumor-promoting mechanism of CTRP6. The present study reviews the role of CTRP6 in tumors of the digestive system and its possible mechanisms. D.A. Spandidos 2022-09-21 /pmc/articles/PMC9533366/ /pubmed/36276484 http://dx.doi.org/10.3892/ol.2022.13511 Text en Copyright: © Zhang et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Review
Zhang, Aimin
Kong, Mowei
Zhang, Xiuyun
Pei, Zhenying
Mechanism of action of CTRP6 in the regulation of tumorigenesis in the digestive system
title Mechanism of action of CTRP6 in the regulation of tumorigenesis in the digestive system
title_full Mechanism of action of CTRP6 in the regulation of tumorigenesis in the digestive system
title_fullStr Mechanism of action of CTRP6 in the regulation of tumorigenesis in the digestive system
title_full_unstemmed Mechanism of action of CTRP6 in the regulation of tumorigenesis in the digestive system
title_short Mechanism of action of CTRP6 in the regulation of tumorigenesis in the digestive system
title_sort mechanism of action of ctrp6 in the regulation of tumorigenesis in the digestive system
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533366/
https://www.ncbi.nlm.nih.gov/pubmed/36276484
http://dx.doi.org/10.3892/ol.2022.13511
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