Adipocyte mesenchymal transition contributes to mammary tumor progression

Obesity is associated with increased cancer incidence and progression. However, the relationship between adiposity and cancer remains poorly understood at the mechanistic level. Here, we report that adipocytes from tumor-invasive mammary fat undergo de-differentiation to fibroblast-like precursor ce...

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Detalles Bibliográficos
Autores principales: Zhu, Qingzhang, Zhu, Yi, Hepler, Chelsea, Zhang, Qianbin, Park, Jiyoung, Gliniak, Christy, Henry, Gervaise H., Crewe, Clair, Bu, Dawei, Zhang, Zhuzhen, Zhao, Shangang, Morley, Thomas, Li, Na, Kim, Dae-Seok, Strand, Douglas, Deng, Yingfeng, Robino, Jacob J., Varlamov, Oleg, Gordillo, Ruth, Kolonin, Mikhail G., Kusminski, Christine M., Gupta, Rana K., Scherer, Philipp E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533474/
https://www.ncbi.nlm.nih.gov/pubmed/36103820
http://dx.doi.org/10.1016/j.celrep.2022.111362

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