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LPAR5 confers radioresistance to cancer cells associated with EMT activation via the ERK/Snail pathway

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) is a critical event contributing to more aggressive phenotypes in cancer cells. EMT is frequently activated in radiation-targeted cells during the course of radiotherapy, which often endows cancers with acquired radioresistance. However, the ups...

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Detalles Bibliográficos
Autores principales:	Sun, Xiao-Ya, Li, Hao-Zheng, Xie, Da-Fei, Gao, Shan-Shan, Huang, Xin, Guan, Hua, Bai, Chen-Jun, Zhou, Ping-Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533496/ https://www.ncbi.nlm.nih.gov/pubmed/36199069 http://dx.doi.org/10.1186/s12967-022-03673-4

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