Cargando…

System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma

BACKGROUND: Pancreatic adenocarcinoma (PAAD) is one of the most common malignant tumors of the digestive tract. Pyroptosis is a newly discovered programmed cell death that highly correlated with the prognosis of tumors. However, the prognostic value of pyroptosis in PAAD remains unclear. METHODS: A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Cheng, Niu, Yandie, Li, Feng, Zhao, Wei, Ma, Liukai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533512/ https://www.ncbi.nlm.nih.gov/pubmed/36199146 http://dx.doi.org/10.1186/s12967-022-03632-z

Ejemplares similares

System analysis based on the cuproptosis-related genes identifies LIPT1 as a novel therapy target for liver hepatocellular carcinoma
por: Yan, Cheng, et al.
Publicado: (2022)

The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8
por: Zhang, Jia-yuan, et al.
Publicado: (2021)

Overexpression of GSDMC is a prognostic factor for predicting a poor outcome in lung adenocarcinoma
por: Wei, Jie, et al.
Publicado: (2020)

System analysis based on the ER stress-related genes identifies WFS1 as a novel therapy target for colon cancer
por: Yang, Xianguang, et al.
Publicado: (2022)

Pyroptosis-related genes GSDMB, GSDMC, and AIM2 polymorphisms are associated with risk of non-small cell lung cancer in a Chinese Han population
por: Zhang, Xia, et al.
Publicado: (2023)

Construction and validation of a prognostic model for lung adenocarcinoma based on endoplasmic reticulum stress-related genes
por: Li, Feng, et al.
Publicado: (2022)

High Expression of GSDMC Is Associated with Poor Survival in Kidney Clear Cell Cancer
por: Cui, Yun-Qian, et al.
Publicado: (2021)

HPV18 E6 inhibits α‐ketoglutarate‐induced pyroptosis of esophageal squamous cell carcinoma cells via the P53/MDH1/ROS/GSDMC pathway
por: Tang, Duo, et al.
Publicado: (2023)

Development of a Prognostic Model Based on Pyroptosis-Related Genes in Pancreatic Adenocarcinoma
por: Su, Kaifeng, et al.
Publicado: (2022)

METTL14-upregulated miR-6858 triggers cell apoptosis in keratinocytes of oral lichen planus through decreasing GSDMC
por: Wang, Xiangyu, et al.
Publicado: (2023)

Values of a novel pyroptosis-related genetic signature in predicting outcome and immune status of pancreatic ductal adenocarcinoma
por: Xu, Xiang, et al.
Publicado: (2022)

Low Back Pain With Persistent Radiculopathy; the Clinical Role of Genetic Variants in the Genes SOX5, CCDC26/GSDMC and DCC
por: Lie, Marie Udnesseter, et al.
Publicado: (2022)

Recent advances in targeted therapy for pancreatic adenocarcinoma
por: Fang, Yu-Ting, et al.
Publicado: (2023)

A novel refined pyroptosis and inflammasome-related genes signature for predicting prognosis and immune microenvironment in pancreatic ductal adenocarcinoma
por: Zuo, Jieliang, et al.
Publicado: (2022)

Pyroptosis-related lncRNA pairs to estimate the molecular features and prognostic outcomes of pancreatic ductal adenocarcinoma
por: Lu, Si-Yuan, et al.
Publicado: (2022)

Novel Pyroptosis-Related Gene Signatures Identified as the Prognostic Biomarkers for Bladder Carcinoma
por: You, Jia, et al.
Publicado: (2022)

Prognostic signature of esophageal adenocarcinoma based on pyroptosis-related genes
por: Li, Guo-Sheng, et al.
Publicado: (2022)

Blood transcriptome analysis revealed the crosstalk between COVID-19 and HIV
por: Yan, Cheng, et al.
Publicado: (2022)

Prognostic significance of pyroptosis-related factors in lung adenocarcinoma
por: Lin, Ximing, et al.
Publicado: (2022)

Construction and comprehensive analysis of a novel prognostic signature associated with pyroptosis molecular subtypes in patients with pancreatic adenocarcinoma
por: Huang, Qian, et al.
Publicado: (2023)

Bioinformatic Analysis of Prognostic Value of Pyroptosis-Related Genes and Its Effect on Immune Cell Infiltration in Pancreatic Adenocarcinoma
por: Wang, Jian, et al.
Publicado: (2022)

The Role of Nonapoptotic Programmed Cell Death — Ferroptosis, Necroptosis, and Pyroptosis — in Pancreatic Ductal Adenocarcinoma Treatment
por: Hsu, Sheng-Kai, et al.
Publicado: (2022)

A novel pyroptosis-related lncRNA signature for prognostic prediction in patients with lung adenocarcinoma
por: Song, Jiahang, et al.
Publicado: (2021)

A novel pyroptosis-related prognostic signature for lung adenocarcinoma: Identification and multi-angle verification
por: Wang, Xinyue, et al.
Publicado: (2023)

Genomic and Immunological Characterization of Pyroptosis in Lung Adenocarcinoma
por: Song, Yaobo, et al.
Publicado: (2022)

A novel pyroptosis related genes signature for predicting prognosis and estimating tumor immune microenvironment in lung adenocarcinoma
por: Wu, Chunting, et al.
Publicado: (2022)

Identification of a Pyroptosis-Related Gene Signature and Effect of Silencing the CHMP4C and CASP4 in Pancreatic Adenocarcinoma
por: Chen, Yajun, et al.
Publicado: (2022)

A Comprehensive Analysis of Pyroptosis-Related lncRNAs Signature Associated With Prognosis and Tumor Immune Microenvironment of Pancreatic Adenocarcinoma
por: Zhao, Kai, et al.
Publicado: (2022)

Molecular alterations and targeted therapy in pancreatic ductal adenocarcinoma
por: Qian, Yunzhen, et al.
Publicado: (2020)

Progress of pyroptosis in acute pancreatitis
por: Li, Hong-Yao, et al.
Publicado: (2021)

A New Definition of Pyroptosis-Related Gene Markers to Predict the Prognosis of Lung Adenocarcinoma
por: Zhang, Guanran, et al.
Publicado: (2021)

Treatment of Severe Acute Pancreatitis and Related Lung Injury by Targeting Gasdermin D-Mediated Pyroptosis
por: Wu, Jinxiang, et al.
Publicado: (2021)

Predicting the Prognosis of Esophageal Adenocarcinoma by a Pyroptosis-Related Gene Signature
por: Zeng, Ruijie, et al.
Publicado: (2021)

Pyroptosis-Related LncRNA Signatures Correlate With Lung Adenocarcinoma Prognosis
por: Huang, Hua, et al.
Publicado: (2022)

Pyroptosis is related to immune infiltration and predictive for survival of colon adenocarcinoma patients
por: Lu, Huiwen, et al.
Publicado: (2022)

Comprehensive analysis of pyroptosis‐related gene signatures for glioblastoma immune microenvironment and target therapy
por: Wang, Zeyu, et al.
Publicado: (2023)

A Novel Pyroptosis-Related Gene Signature for Predicting the Prognosis and the Associated Immune Infiltration in Colon Adenocarcinoma
por: Chen, Zhiyuan, et al.
Publicado: (2022)

Dissection of pyroptosis-related prognostic signature and CASP6-mediated regulation in pancreatic adenocarcinoma: new sights to clinical decision-making
por: Zhu, Jun, et al.
Publicado: (2023)

A Pyroptosis-Related Signature Predicts Overall Survival and Immunotherapy Responses in Lung Adenocarcinoma
por: Zhu, Kaibin, et al.
Publicado: (2022)

Revealing novel pyroptosis-related therapeutic targets for sepsis based on machine learning
por: Chen, Ying, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_khkpl5srbbohp85bvm0fo68v8p